• emanuele.bruni@unicamillus.org

Emanuele Bruni

Applied Biology - Bio/13

Biography

He obtained a Bachelor’s Degree in Cellular and Molecular Biology, a Specialist Degree in Biology and Human Evolution cum Laude and a PhD in Cellular and Molecular Biology at the University of Rome “Tor Vergata”, where he also obtained a Master’s degree level in Personalized Nutrition cum Laude and qualification as a Specialist Biologist.

In the University of Rome “Tor Vergata” he continues his professional training with post-graduate grants, expanding his technical skills with an internship in Luxembourg, at the Laboratory of Cellular and Molecular Biology directed by Prof. Diederich and an internship in Germany, at the Laboratory directed by Prof. Grassingher at the University Hospital of Regensburg, to learn the techniques for setting up and maintaining stroma/cells co-cultures.

From January 2024 to date he has obtained a post-doc research contract at the Experimental Immunology Laboratory of the Istituto Dermopatico dell’Immacolata (IDI-IRCCS) in Rome, entitled: “Characterization of new bioinks composed of self-assembling peptides for the bioprinting of skin equivalents”.

From July 2023 to December 2023 he obtained a post-doc research contract at the Experimental Immunology Laboratory of the Istituto Dermopatico dell’Immacolata (IDI-IRCCS)

in Rome, entitled: “Mechanisms of response to immunotherapy with checkpoint inhibitors immunological in skin tumors”.

From January 2023 to June 2023 he obtained a post-doc research contract at the Experimental Immunology Laboratory of the Istituto Dermopatico dell’Immacolata (IDI-IRCCS) in Rome, entitled: “The immune response in skin tumors: molecular mechanisms and validation of new therapeutic targets and prognostic markers”.

From September 2022 to December 2022 he obtained a post-doc research contract at the Experimental Immunology Laboratory of the Istituto Dermopatico dell’Immacolata (IDI-IRCCS) in Rome, entitled: “3D bioprinting of human skin and squamous cell tumors as advanced models for precision medicine”.

In the A.Y. 2019/2020 obtained a research grant at the University of Rome “Tor Vergata”, at the Applied Biology Laboratory, under the scientific direction of Prof. Lina Ghibelli, entitled: “Effect of natural compounds and metabolic modulators in repopulation post-therapy tumor”.

From the A.A. 2017/2018 to date you have obtained the teaching position at the Catholic University “Nostra Signora del Buon Consiglio” of Tirana, for the chair of Biology in the Integrated Course of Biology and Genetics, for the Degree Course in Medicine and Surgery.

From the A.A. 2015/2016 to date you carry out teaching / seminar activities in the “Applied Biology” module at the School of Specialization in Medical Physics at the University of Rome “Tor Vergata”.

From the A.A. 2016/2017 to date she carries out teaching support activities and participates as a member of the exam commission, in the English language course of Nanobiotechnology, Degree Course in Biotechnology, at the University of Rome “Tor Vergata”.

His research activities is focused in the preparation of some matrices, and their use, in the bioprinting of human skin constructs made up of human fibroblasts and keratinocytes. He is also involved in developing alternative techniques for incorporating squamous cell carcinoma cells into bioprinted skin constructs by obtaining spheroids from cell lines.

He study also the immune response to immunotherapy with immunological checkpoint inhibitors in skin tumors.

During the years he has been involved in the identification of anti-tumor therapies, studying both the physiological mechanisms of apoptotic induction and the effect of cytotoxic treatments (high doses of drugs) and metronomic therapy (low doses of chemotherapeutic agents) on growth and repopulation of tumor cells and the study of the anti-tumor effects of natural compounds, the anti-apoptotic effect of static and pulsating magnetic fields on biological systems and the biological effects of nanoparticles.